Уход по типу "кенгуру" улучшает выживаемость детей с низким весом при рождении.

Большое интервенционное исследование в Индии показало более низкую неонатальную смертность и лучшие результаты роста глубоко недоношенных детей при раннем и тесном контакте с матерью.

Несмотря на то, что уход по типу "кенгуру" (контакт кожа-к-коже между родителем и младенцем) множеством исследований признан полезным для новорожденных, он пока не приобрёл повсеместного применения. В рандомизированном контролируемом исследовании, проведенном в Индии, исследователи сравнили неонатальную (до 28 дней жизни) смертность среди 8402 детей с массой тела от 1500 до 2250 г, получавших либо ежедневный уход по типу "кенгуру",  либо обычный уход за новорожденным, подразумевающий контакт матери и ребёнка только во время кормления. Уход по типу "кенгуру" начинался в течение 72 часов после рождения (в среднем в течение 30 часов) и длился не менее 11 часов в день. Результаты в возрасте 28 дней были следующими: смертность была значительно ниже среди младенцев, получавших  уход по типу "кенгуру"(1,6% против 2,3%) как в целом, так и среди подгрупп по массе тела при рождении. Средний возраст выживших младенцев увеличивался с увеличением продолжительности ежедневного контакта кожа-к-коже с матерью. В группе с уходом по типу "кенгуру" значительно чаще отмечалось исключительно грудное вскармливание. В этой же группе коэффициент длины и массы тела новорожденных были выше, а частота серьёзных бактериальных инфекций и диареи - ниже.

Источник: Lancet. 2019 Oct 4. pii: S0140-6736(19)32223-8. doi: 10.1016/S0140-6736(19)32223-8. [Epub ahead of print]

 

Effect of community-initiated kangaroo mother care on survival of infants with low birthweight: a randomised controlled trial.

Mazumder S et al

BACKGROUND:

Coverage of kangaroo mother care remains very low despite WHO recommendations for its use for babies with low birthweight in health facilities for over a decade. Initiating kangaroo mother care at the community level is a promising strategy to increase coverage. However, knowledge of the efficacy of community-initiated kangaroo mother care is still lacking. We aimed to assess the effect of community-initiated kangaroo mother care provided to babies weighing 1500-2250 g on neonatal and infant survival.

METHODS:

In this randomised controlled, superiority trial, undertaken in Haryana, India, we enrolled babies weighing 1500-2250 g at home within 72 h of birth, if not already initiated in kangaroo mother care, irrespective of place of birth (ie, home or health facility) and who were stable and feeding. The first eligible infants in households were randomly assigned (1:1) to the intervention (community-initiated kangaroo mother care) or control group by block randomisation using permuted blocks of variable size. Twins were allocated to the same group. For second eligible infants in the same household as an enrolled infant, if the first infant was assigned to the intervention group the second infant was also assigned to this group, whereas if the first infant was assigned to the control group the second infant was randomly assigned (1:1) to the intervention or control group. Mothers and infants in the intervention group were visited at home (days 1-3, 5, 7, 10, 14, 21, and 28) to support kangaroo mother care (ie, skin-to-skin contact and exclusive breastfeeding). The control group received routine care. The two primary outcomes were mortality between enrolment and 28 days and between enrolment and 180 days. Analysis was by intention to treat and adjusted for clustering within households. The effect of the intervention on mortality was assessed with person-time in the denominator using Cox proportional hazards model. This study is registered with ClinicalTrials.gov, NCT02653534 and NCT02631343, and is now closed to new participants.

FINDINGS:

Between July 30, 2015, and Oct 31, 2018, 8402 babies were enrolled, of whom 4480 were assigned to the intervention group and 3922 to the control group. Most births (6837 [81·4%]) occurred at a health facility, 36·2% (n=3045) had initiated breastfeeding within 1 h of birth, and infants were enrolled at an average of about 30 h (SD 17) of age. Vital status was known for 4470 infants in the intervention group and 3914 in the control group at age 28 days, and for 3653 in the intervention group and 3331 in the control group at age 180 days. Between enrolment and 28 days, 73 infants died in 4423 periods of 28 days in the intervention group and 90 deaths in 3859 periods of 28 days in the control group (hazard ratio [HR] 0·70, 95% CI 0·51-0·96; p=0·027). Between enrolment and 180 days, 158 infants died in 3965 periods of 180 days in the intervention group and 184 infants died in 3514 periods of 180 days in the control group (HR 0·75, 0·60-0·93; p=0·010). The risk ratios for death were almost the same as the HRs (28-day mortality 0·71, 95% CI 0·52- 0·97; p=0·032; 180-day mortality 0·76, 0·60-0·95; p=0·017).

INTERPRETATION:

Community-initiated kangaroo mother care substantially improves newborn baby and infant survival. In low-income and middle-income countries, incorporation of kangaroo mother care for all infants with low birthweight, irrespective of place of birth, could substantially reduce neonatal and infant mortality.

PubMed

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